ISSN: 0300-8932 Factor de impacto 2023 7,2
Vol. 5. Núm. D.
Páginas 30D-37D (Octubre 2005)

Síndrome metabólico: retos y esperanzas
Síndrome metabólico y diabetes mellitus

Metabolic Syndrome and Diabetes Mellitus

Enrique González Sarmientoa¿Isaac Pascual CallejabMartín Laclaustra GimenobJosé A. Casasnovas Lenguasb

Opciones

La diabetes mellitus (DM) es una enfermedad metabólica crónica que está adquiriendo en los últimos años proporciones de auténtica epidemia. Se asocia frecuentemente con obesidad, alteraciones del metabolismo lipídico y proteínico, así como con hipertensión arterial y otros factores de riesgo cardiovascular, lo que constituye el síndrome metabólico. La DM tipo 2 (DM2) es un factor de riesgo importante para la enfermedad coronaria y la aterosclerosis precoz. Su etiopatogenia es multifactorial y está muy relacionada con la resistencia insulínica (RI), que es el proceso fisiopatológico común al conjunto de factores de riesgo cardiovascular. Respecto a la prevención y el tratamiento de la DM2, es fundamental la modificación del estilo de vida, con especial hincapié en la alimentación equilibrada y la introducción del ejercicio físico aeróbico en la vida cotidiana. Cuando las pautas higiénico- dietéticas no son suficientes, se debe recurrir a fármacos que actúen sobre la diana de la resistencia insulínica, como la metformina y las tiazolidinas.

Palabras clave

Diabetes mellitus tipo 2
Síndrome metabólico
Riesgo cardiovascular
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