Revista Española de Cardiología (English Edition) Revista Española de Cardiología (English Edition)
Rev Esp Cardiol. 2002;55:292-302 - Vol. 55 Num.03

Molecular genetics of cadiomyopathies

Robert Roberts a

a Sección de Cardiología. Baylor College of Medicine. Houston. Texas. EE.UU.

Keywords

Hypertrophic cardiomyopathy. Dilated cardiomyopathy. Genetics. Sudden cardiac death.

Abstract

In the last decade our understanding of cardiac pathophysiology has experienced significant advances linked to major advances in molecular genetics. Although many genes are associated today with cardiac diseases, the genetics of both hypertrophic cardiomyopathy and dilated cardiomyopathy have generated great interest. The familial nature of the disease in some patients has been very useful in this regard. In addition, there are also excellent experimental models to study the implications of the genetic abnormalities. Altogether the study of the molecular genetics of the cardiomyopathies should provide not only prognostic information but also new therapeutic alternatives.

1885-5857/© 2002 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved

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