Revista Española de Cardiología (English Edition) Revista Española de Cardiología (English Edition)
Rev Esp Cardiol. 2006;59:136-42 - Vol. 59 Num.02 DOI: 10.1016/S1885-5857(06)60122-9

Left Ventricular Hypertrophy in the Spanish Hypertensive Population. The ERIC-HTA Study

José V Lozano a, Josep Redón b, Luis Cea-Calvo c, Cristina Fernández-Pérez d, Jorge Navarro e, Álvaro Bonet e, Jorge González-Esteban c

a Centro de Salud Serrería 2, Valencia, España,
b Unidad de Hipertensión Arterial, RECAVA, Hospital Clínico Universitario, Universidad de Valencia, Valencia, España,
c Departamento de Investigación Clínica, Merck Sharp & Dohme de España, Madrid, España,
d Unidad de Apoyo a la Investigación, Hospital Clínico Universitario San Carlos, Universidad Complutense de Madrid, Madrid, España,
e Centro de Salud Salvador Pau, Valencia, España,

Keywords

Hypertension. Left ventricular hypertrophy. Cardiovascular risk. Blood pressure control.

Abstract

Introduction and objectives. Left ventricular hypertrophy (LVH) is the earliest manifestation of cardiac damage in hypertension. Its appearance is associated with a poor cardiovascular prognosis. The objectives of this study were to determine the prevalence of electrocardiographic LVH and to assess the epidemiological characteristics of hypertensive patients receiving primary care. Patients and method. A cross-sectional multicenter study of hypertensive patients aged 55 years or more was carried out in a primary care setting. Blood pressure was measured using the standard method. Cardiovascular history was determined from medical records and LVH was assessed electrocardiographically using Cornell's criteria. Results. In total, 15 798 patients (mean age 68.0 years, 55.3% women, and 30.4% with diabetes mellitus) were evaluated. Of these, 3207 (20.3%) had electrocardiographic signs of LVH. The prevalence was higher in males, diabetics, smokers, and patients with high blood pressure or renal or cardiovascular disease. Compared to patients without LVH, those with the condition were older, were more often male, and were more likely to have diabetes or renal or cardiovascular disease. Multivariate analysis showed that LVH was independently associated with advanced age, male gender, diabetes, smoking, poor blood pressure control, and the presence of cardiovascular or renal disease. Blood pressure control was poorer in patients with LVH than in those without it. Conclusions. The prevalence of electrocardiographic LVH is high, with affected patients being more likely to have diabetes or renal or cardiovascular disease. Moreover, blood pressure control is poor in these patients, and more aggressive pharmacological management is needed.

1885-5857/© 2006 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved

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