Revista Española de Cardiología (English Edition) Revista Española de Cardiología (English Edition)
Rev Esp Cardiol. 2002;55:432-7 - Vol. 55 Num.04

Genetics and Arrhythmias

Ramon Brugada a, Josep Brugada b, Pedro Brugada c

a aylor College of Medicine. Houston. Texas. EE.UU.
b Unitat d'Arrítmies. Universitat de Barcelona.
c Cardiovascular Research and Teaching Institute Aalst. Bélgica.

Keywords

Genetics. Arrhythmias. Sudden death. Molecular biology.

Abstract

In the last 50 years we have been very successful at prolonging survival and improving the quality of life of patients with cardiac disease. The innovations in technology and pharmacology, better preventive and diagnostic tools have provided tremendous breakthroughs. However, despite our best efforts, the majority of cardiac diseases are structural in origin and will progress to their ultimate outcome. Curative therapies are not available due in part to our poor understanding of the basic mechanisms responsible for these diseases. The new developments in molecular genetics and biology are likely to change the way we approach a cardiac patient in the future. The diseases are presently being deciphered at the most basic level, and the information obtained opens new possibilities not only for better therapeutic and diagnostic measures but also for prevention of the disease.

1885-5857/© 2002 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved

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