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Revista Española de Cardiología (English Edition) Revista Española de Cardiología (English Edition)
Rev Esp Cardiol. 2018;71:162-9 - Vol. 71 Num.03 DOI: 10.1016/j.rec.2017.04.010

Timing of Onset and Outcome of New Conduction Abnormalities Following Transcatheter Aortic Valve Implantation: Role of Balloon Aortic Valvuloplasty

Francisco Campelo-Parada a, Luis Nombela-Franco b, Marina Urena a,c, Ander Regueiro a, Pilar Jiménez-Quevedo b, María Del Trigo a, Chekrallah Chamandi a, Tania Rodríguez-Gabella a, Vincent Auffret a, Omar Abdul-Jawad Altisent a, Robert DeLarochellière a, Jean-Michel Paradis a, Eric Dumont a, François Philippon a, Nicasio Pérez-Castellano b, Rishi Puri a, Carlos Macaya b, Josep Rodés-Cabau a,

a Department of Cardiology, Quebec Heart and Lung Institute, Quebec City, Canada
b Departamento de Cardiología, Hospital Clínico San Carlos, Madrid, Spain
c Department of Cardiology, Bichat Claude Bernard Hospital-Paris VII University, Paris, France


Aortic stenosis. Transcatheter aortic valve implantation. Left bundle branch block. Pacemaker. Conduction disturbances. Conduction abnormalities. Direct transcatheter aortic valve implantation. Balloon aortic valvuloplasty.


Introduction and objectives

Little is known about the timing of onset and outcome of conduction abnormalities (CA) following balloon-expandable transcatheter aortic valve implantation. The aim of this study was to examine the timing of CA and determine the impact of balloon aortic valvuloplasty (BAV) on the persistence of these abnormalities.


A total of 347 patients were included. Of these, 75 had a continuous electrocardiogram recording and a 6-lead electrocardiogram at each step of the procedure.


In the transcatheter aortic valve implantation population undergoing continuous electrocardiogram monitoring, new-onset left bundle branch block (LBBB) or third-degree atrioventricular block occurred in 48 (64%) and 16 (21.3%) patients, with 51.5% of CA occurring before valve implantation. Left bundle branch block persisted more frequently at hospital discharge (53.8 vs 22.7%; P = .028) and at 1-month follow-up (38.5 vs 13.6%; P = .054) when occurring before valve implantation. Balloon aortic valvuloplasty prior to valve implantation was used in 264 (76.1%) patients, and 78 (22.5%) had persistent LBBB or complete atrioventricular block requiring pacemaker implantation. Persistent LBBB or unresolved atrioventricular block at 1 month occurred more frequently in the BAV group (76.1 vs 47.6%; P = .021), and the use of BAV was associated with a lack of CA resolution (OR, 3.5; 95%CI, 1.17-10.43; P = .021).


In patients undergoing a balloon-expandable transcatheter aortic valve implantation, more than half of CA occurred before valve implantation. Early occurrence of CA was associated with a higher rate of persistence at 1-month follow-up. The use of BAV was associated with an increased risk of CA persistence.


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1885-5857/© 2018 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved